Antimalarial Drug Discovery
In collaboration with Professors Roepe and DeDios (both Chemistry Department at Georgetown University) we are pursuing a rational drug design program ...

Dynamic Stereochemistry
The development of mechanistic insights into isomerization reactions and information about the conformational and configurational stability...

Solid State Chemistry
Supramolecular self-assembly has become a widely recognized tool for the formation of well-defined noncovalent arrangements of organic building blocks...

Asymmetric Catalysis
Most biologically active compounds - flavors, nutrients, agrochemicals, pharmaceuticals - are chiral and more than 50 % of today's top selling drugs are single enantiomers ...

Stereoselective Fluorescence and UV-Vis Sensing of Chiral Compounds
We have developed highly constrained C₂-symmetric diheteroarylnaphthalenes that undergo stereoselective interactions with a variety of chiral compounds, resulting...

Transition Metal Catalysis and Cross-Coupling Reactions
Recent efforts have provided highly active transition metal catalysts that allow one to replace aryl iodides...